If you haven't seen it already, I think it is a great show. You can view it online at ABC.com under full shows. In fact, I recommend it as there are far fewer commercials and you can pause it when you want to get up.
The hot red-headed Dr Addison Shepherd (Kate Walsh) is going to be leaving the show for an offshoot which was previewed in this past weeks 2hr special (82 minutes online which means 38 minutes of commercials on regular TV) Not sure if the new series is going to be worthwhile with the exception that Kate Walsh will be on there.
Apparently Preston Burke (Isaiah Washington) won't be returning next season. However, I think he adds more to the show than does his fiance Cristina. I think she is just annoying and would rather see her leave the show.
The whole George/Callie/Izzy thing... He loves both, they both love him... Legalized polygamy would solve that whole problem.